제목

Functional screening of  Asparagus officinalis  L. stem and root extracts

게재지

Korean J. Food Sci. Technol( 한국식품과학회지 )

발행일

2021 년 2 월호 , 53; p46-54

Abstract

The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 μ g/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 μ g/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 μ g/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.